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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL14
All Species:
2.12
Human Site:
S219
Identified Species:
4.24
UniProt:
Q8N1E6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1E6
NP_689654.1
418
45886
S219
C
Q
K
L
T
D
L
S
L
K
H
I
S
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117874
404
44252
T208
C
L
G
L
E
Q
L
T
L
Q
D
C
Q
K
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BID8
400
43846
L204
A
A
E
G
C
L
G
L
E
Q
L
T
L
Q
D
Rat
Rattus norvegicus
Q5MJ12
479
51833
E224
M
Q
G
V
V
R
L
E
L
S
G
C
N
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425498
333
36281
L137
A
A
E
G
C
L
G
L
E
Q
L
T
L
Q
D
Frog
Xenopus laevis
NP_001083845
400
43783
L204
A
A
E
G
C
L
S
L
E
Q
L
T
L
Q
D
Zebra Danio
Brachydanio rerio
NP_001015043
400
44429
L204
A
A
E
G
C
L
S
L
E
Y
L
T
L
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523812
538
58367
F337
G
I
G
H
L
A
G
F
S
R
E
T
A
E
G
Honey Bee
Apis mellifera
XP_393659
481
52936
V280
G
I
A
H
L
A
G
V
N
R
E
A
A
G
G
Nematode Worm
Caenorhab. elegans
P34284
466
52046
V219
D
A
I
Q
D
R
G
V
Q
I
I
L
S
N
C
Sea Urchin
Strong. purpuratus
XP_784778
450
49952
V249
G
I
G
Y
L
A
G
V
S
V
E
A
A
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5D2
610
66404
G260
S
E
Y
I
H
D
K
G
L
I
A
V
A
Q
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.6
N.A.
N.A.
95.6
21.2
N.A.
N.A.
75.5
90.6
88.7
N.A.
46.2
54
25.5
63.5
Protein Similarity:
100
N.A.
96.6
N.A.
N.A.
95.6
37.1
N.A.
N.A.
77.9
93
92.1
N.A.
58.3
65.9
43.1
73.3
P-Site Identity:
100
N.A.
26.6
N.A.
N.A.
0
20
N.A.
N.A.
0
0
0
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
N.A.
46.6
N.A.
N.A.
20
33.3
N.A.
N.A.
20
20
13.3
N.A.
20
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
26
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
42
9
0
0
25
0
0
0
0
9
17
34
0
0
% A
% Cys:
17
0
0
0
34
0
0
0
0
0
0
17
0
0
9
% C
% Asp:
9
0
0
0
9
17
0
0
0
0
9
0
0
9
34
% D
% Glu:
0
9
34
0
9
0
0
9
34
0
25
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
25
0
34
34
0
0
50
9
0
0
9
0
0
9
42
% G
% His:
0
0
0
17
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
25
9
9
0
0
0
0
0
17
9
9
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
0
9
0
0
0
9
0
% K
% Leu:
0
9
0
17
25
34
25
34
34
0
34
9
34
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
9
0
9
0
0
9
34
0
0
9
42
0
% Q
% Arg:
0
0
0
0
0
17
0
0
0
17
0
0
0
17
0
% R
% Ser:
9
0
0
0
0
0
17
9
17
9
0
0
17
0
0
% S
% Thr:
0
0
0
0
9
0
0
9
0
0
0
42
0
0
0
% T
% Val:
0
0
0
9
9
0
0
25
0
9
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _